Hamlin collapsed after tackling Bengals receiver Tee Higgins midway through the first quarter of Monday's game and underwent CPR for approximately 10 minutes before he was taken to the University of Cincinnati Medical Center.

"Per the physicians caring for Damar Hamlin at the University of Cincinnati Medical Center, Damar has shown remarkable improvement over the past 24 hours," the statement said.

"While still critically ill, he has demonstrated that he appears to be neurologically intact. His lungs continue to heal and he is making steady progress.

"We are grateful for the love and support we have received."

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NFL Network's Ian Rapoport reported that Hamlin opened his eyes on Wednesday night and has been able to grip the hands of those with him.

The Bills had stated earlier on Wednesday that Hamlin was showing signs of improvement but remained in critical condition in the ICU.

An incredible league-wide response has seen coaches and players pay tribute to the 24-year-old, whose toy drive GoFundMe page set up in 2020 as part of his Chasing M's Foundation has seen donations eclipse an initial target of $2,500 by reaching upwards of $7m.

"The outpouring of support for Damar across the nation has been amazing," said Hamlin's representation Agency 1 Sports on Thursday. "Thank you for the calls, messages and emails.

"Damar has made substantial improvement overnight. We are so thankful for all of the first responders, doctors and hospital staff and every one who has played a role in this process.

"Please continue to pray for Damar and we will provide updates as they are available."

The NFL are currently in talks over whether or not they will resume Monday's Bills-Bengals game, which was postponed in light of Hamlin's collapse, though the league did announce that any prospective resumption would not take place this week.

Hamlin is in his second season in the NFL, after being taken in the sixth round of the 2021 NFL Draft by the Bills. He spent five years playing college football at Pittsburgh, his hometown, appearing in 48 games for the Panthers.

He has started 14 games for the Bills this season in place of injured safety Micah Hyde, who suffered a neck injury in Week Two and has been on injured reserve since. Hamlin is tied for the second-most tackles on the team this year, with 91.