The pair's withdrawal from the squad follows on from the loss of Tom Curry last week after he also sustained a concussion in the opening Test defeat.

Underhill was forced off in the second half at Suncorp Stadium following a tackle on Marika Koroibete, while Itoje's absence for the final contest had already been confirmed by head coach Eddie Jones after he exited before half-time on the back of a collision with Hunter Paisami.

In a statement Rugby Football Union confirmed that no replacements will be called up for the pair.

The decisions made regarding both are reflective of updated return-to-play protocols introduced at the start of the month.

Northampton Saints skipper Lewis Ludlam and Leicester Tigers lock Ollie Chessum look set to start in the third Test after coming off the bench in the first two meetings.

England's concerns at flanker have been partially eased by the news that Jack Willis is available to train after pulling out from the bench at the weekend due to a rib problem.

England's decider will be played in Sydney on Saturday, with coverage live on Sky Sports Action from 10:15am and kick-off at 10:55am.

The contest forms part of a busy day of rugby live on Sky Sports, with Ireland, Wales and Scotland also playing in deciders against New Zealand, South Africa and Argentina respectively.

Summer Tours on Sky Sports

Every deciding Test is live on Sky Sports across the day on Saturday, as the Northern Hemisphere teams all aim to replicate the success they achieved last weekend.

The action on Saturday will start with Ireland in Wellington, before moving to Sydney for England's contest against the Wallabies.

Mid-afternoon, the focus turns to Cape Town and Wales' quest to win back-to-back Tests against South Africa and the day will finish with Scotland in Santiago del Estero, Argentina.

• New Zealand vs Ireland in Wellington - coverage from 7.30am (8:05am kick-off)
• Australia vs England in Sydney - coverage from 10:15am (10:55am kick-off)
• South Africa vs Wales in Cape Town - coverage from 3.30pm (4.05pm kick-off)
• Argentina vs Scotland in Santiago del Estero - coverage from 7.30pm (8.10pm kick-off)

Watch all of the action from the Summer Tours on Saturday, with coverage live on Sky Sports Action from 7.30am. Ireland, England, Wales and Scotland all have chances to clinch series wins over Southern Hemisphere opponents.